Some studies suggest that pomegranates may help fight inflammation in the gut. There are also studies that demonstrate the anti-inflammatory potential of punicic acid from pomegranate seed oil against breast cancer cells. Researchers posited that since the compounds in pomegranates have anti-inflammatory effects, the fruit could be used to treat arthritis. Data from laboratory studies suggested that pomegranate extracts can block enzymes that are known to damage the joints of individuals diagnosed with osteoarthritis, as previously noted. Here Darnel Fernandez, NaturalNews, reflects on recent study of pomegranate anti-aging benefits:

“The pomegranate, scientifically known as Punica granatum, is a popular deciduous shrub, thanks to its ruby-red fruit. Considered among the healthiest fruits around, the pomegranate is packed with polyphenols and antioxidants that help deal with a variety of health problems like high blood pressure and atherosclerosis. While previous studies have established that eating a pomegranate could help slow down the aging process, a recent study revealed that a particular compound in the fruit could be responsible for its anti-aging benefits.

The paper, which was published in the journal Nature Metabolism, is the first-ever in-human clinical trial suggesting the supplementation of urothilin A for its anti-aging benefits, mainly due to its influence on mitochondrial and cellular health. Urothilin A is a natural dietary, microflora-derived metabolite found in pomegranate and other foods. This metabolite was shown to stimulate mitophagy — the targeted degradation of damaged mitochondria — and improve muscle health in older animals.

“There are currently no effective solutions to treat age-related decline in muscle function other than months of exercise. This is an important first clinical validation that shows Urolithin A could be a promising solution for the management of healthy muscle function during aging,” said Roger Fielding, a professor at Tufts University who was not involved in the study.

The secret behind pomegranate’s anti-aging powers

Pomegranate, a fruit prized by several civilizations for its large arsenal of health benefits, contains polyphenols called ellagitannins. When ingested into the body, the polyphenols are converted into urolithin A inside the gut.”

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