Red sage is a plant used in traditional Chinese Medicine. It goes by other names and commonly called Chinese sage. It is a perennial plant in the genus salvia, highly valued for its roots. Here Michelle Simmons, Herbs.news, reflects on the protection offered by the extract of red sage in treating diabetic kidney disease:
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“Diabetic nephropathy, also known as diabetic kidney disease, is a serious complication that can cause chronic kidney disease and end-stage renal disease. This complication is said to be triggered by oxidative stress. Fortunately, researchers from China and Sri Lanka found that this complication can be attenuated with red sage (Salvia miltiorrhiza), or danshen in Chinese medicine, which possesses strong antioxidant properties.
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For the study, the researchers evaluated the kidney-protective effect of red sage extract against diabetic nephropathy and analyzed the underlying molecular mechanism in an experimental diabetic nephropathy model. They treated mouse mesangial cells with a highdose of glucose and treated mice with streptozotocin to imitate the hyperglycemic conditions in people with diabetic nephropathy.
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The results showed that the treatment with red sage extract reduced metabolic abnormalities linked to hyperglycemic conditions in the experimental diabetic nephropathy model. In streptozotocin-induced mice, red sage extract treatment enhanced renal function, attenuated albuminuria – a symptom of kidney disease – and mitigated the pathological alterations within the glomerulus, a cluster of capillaries around the end of a kidney tubule. In addition, red sage extract also inhibited high glucose-induced reactive oxygen species both in the cells and mice.
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Overall, the findings of the study, which were published in The American Journal of Chinese Medicine, suggest that red sage extract may be used to protect the kidneys against diabetic nephropathy due to its powerful antioxidant properties.”
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Read More … Article Source: https://www.herbs.news/2019-03-31-red-sage-protect-against-diabetic-nephropathy.html
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