People trying to lose weight opt for dietary supplements as they seem to be a safer and more effective alternative to prescription weight loss drugs. Green coffee bean extract, the less processed version of coffee, is commonly used for this purpose.
Green coffee beans are raw, unroasted coffee beans. The beans contain many bioactive compounds, including chlorogenic acid and caffeine. Chlorogenic acid is the main component of green coffee beans, and most of it is removed when the beans are roasted. It is said to be responsible for green coffee’s weight loss effects. Here Virgilio Marin, NaturalNews.com, explores coffee bean extracts and the ability to fight chronic disease:
“Coffee bean extract contains anti-inflammatory compounds that can help fight chronic health problems, according to a study published in the journal Food and Chemical Toxicology.
Researchers from the University of Illinois at Urbana-Champaign and the Autonomous University of Madrid treated fat cells of mice with water-based extracts from coffee bean skins. The researchers found
that the phenolic compounds, protocatechuic acid and gallic acid, reduced fat-induced inflammation and improved glucose absorption and insulin sensitivity.
The researchers suggest that adding these phenolic compounds to one’s diet may work as a nutritional strategy for preventing obesity-related chronic conditions, such as Type 2 diabetes and cardiovascular disease.
Exploring the effects of coffee bean compounds on fat cells
Coffee by-products like the husk and silverskin are generated in large amounts during the harvesting and processing of green, or raw, coffee beans. These by-products contain significant amounts of antioxidants that can be recovered for use as value-added products. Previous studies show that the phenolic compounds in coffee by-products can increase insulin secretion by beta cells and protect the pancreas from oxidative stress.
However, the researchers noted that the anti-inflammatory effect of coffee by-products on adipocytes (fat cells) and their mechanism of action hadn’t been detailed before.
The team tested the effect of five pure phenolics found in coffee husk and silverskin on adipocytes and immune response cells called macrophages. These two types of cells work together in a loop in obesity-related inflammation, which increases oxidative stress and interferes with glucose uptake.”
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